The Merit-based Incentive Payment System (MIPS) continues to evolve, bringing new challenges and opportunities for clinicians aiming to optimize their performance and meet the Centers for Medicare and Medicaid Services (CMS) reporting requirements. As in past years, success with MIPS in 2025 will require a proactive strategy, careful planning, and timely data collection throughout the year. In this article, we’ve outlined a step-by-step checklist to help your practice stay organized, reduce reporting burdens, and achieve success with 2025 MIPS.