CMS will sunset the Web Interface after the 2024 performance year, so this will no longer be a data submission option going forward for Accountable Care Organizations (ACOs). Beginning in 2025 ACOs participating in the Medicare Shared Saving Program (MSSP) will be required to report on all-payer eCQM/CQM MIPS measures established under the new APM Performance Pathway (APP). While these changes will present some challenges for ACOs, this article provides tips to help prepare for the end of the Web Interface and to support compliance with the new reporting requirements.